It's very do-able. But would be hard. I also don't think it would happen. Which is sad cause I think this would be a lot of fun to watch. Sarge and Giggs, Cabbose and Wade or whatever. hehe Tex and Cathrine... I'd love it.
That might be a really funny movie actually. It could start out just like the first Red vs. Blue episode where they ask do you ever wonder why we're here. Then as they're doing that Wade(or Durnt) would appear and start saying that it was like totally a party man. "Wait you see the Blues over there and you automatically think party?"
I think it would be very doable. I think it'd be easier to use the SIMs 2 engine, though. There are enough modders out there (some have even attempted to make the Red vs. Blue guys for download) that the RT guys could find someone easy enough, unless they've stumbled into the modding world of the SIMs. I see the whole thing as a one episode special or a short mini series. I don't think it could work as a long term series. But it'd be funny to see just how it would come together.
Actually, its kinda funny you mention that. If you watch the series closely, and listen, you'll hear things from RvB. Also, one of the theaters at the end of the series when they are talking about how Hollywood ran out of ideas, one of the theaters had Sargent writen in neon lights.