This game and the new Alien Vs Predator game are the only two things out of E3 I'm looking forward to. Probably because they are the only thing that I haven't played before in a previous iteration (well, not so much for the new AvP). A Warhammer 40k action RPG is something that hasn't been done before, and anyone interested in the IP should definitely check it out.

Pros:
SPESS MEHREENS!!!
RPGness
Up close and personal action

Cons:
Ultramarines (nothing against Ultramarines really, they just seem like the default Space Marine Chapter people go with)
Orkz again :/
Very early in production >.<

www.youtube.com/watch?v=gvjICeeoPAU